Most of the research on shiitake mushrooms and cancer has been conducted on laboratory animals or on individual cells in a laboratory setting and has involved mushroom extracts rather than whole mushrooms in food form. For this reason, our understanding of the anti-cancer benefits of shiitake mushrooms as a whole, natural food is still preliminary. But based on research to date, we believe that adding shiitake mushrooms to your diet is likely to offer you anti-cancer benefits, especially with respect to prevention of prostate cancer, breast cancer, and colon cancer.
Medicinal extracts from shiitake mushrooms have been studied much more extensively than the whole food itself. In cell and laboratory animal experiments, numerous components of shiitake mushrooms have been show to help block tumor growth, sometimes by triggering programmed cell death (apoptosis) in the cancer cells. These components have been collectively referred to as "anti-tumor mycochemicals" provided by shiitake mushrooms. Researchers have speculated that more than 100 different types of compounds in shiitake mushrooms may work together to accomplish these anti-tumor results. While the unique polysaccharides in shiitake mushrooms were first thought to be its primary anti-cancer compounds, scientists are now convinced that shiitake provides many non-polysaccharide substances that have anti-tumor effects.
Many shiitake supplements recommend a dosage of around 500 mg or 1500 mg. This is quite a variation so what is the ideal dosage? It is thought that the ideal dosage is 1000 mg of shiitake extract per day to see positive appetite-suppressing results.
Of course there are many variables that enter the equation. You body size, weight, health and metabolic rate will all come into play. You may require more or even less than the 1000 mg. Most guidelines on this recommend that you start out at the lower limits – say around 500mg and then judge the results for yourself. If you are happy that your appetite is lowered then you might want to stick to this dosage. If you are not happy you may want to increase the dosage. It should take a few days for you to see or feel the results so reserve judgment until then.
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